![]() If you’re required to take a drug test, you may be wondering what the results mean and what the different terms on the drug test report indicate. ^ Detection time of drugs of abuse in urine.Drug testing is a common practice in many industries, including healthcare, transportation, and manufacturing.^ The metabolism and urinary excretion in man of phentermine, and the influence of N‐methyl and p‐chloro‐substitution.^ Phentermine Prescribing Information.^ Urine Drug Screening: Practical Guide for Clinicians.The most commonly reported side effects of phentermine include: The onset of action is quick, between 15-30 minutes after taking a dose and has a duration of action ranging from 12 to 14 hours (for the 30 and 37.5 mg capsules/tablets). Afternoon/evening administration should be avoided due to the risk of insomnia. It is typically dosed before breakfast or 1 to 2 hours after breakfast. ![]() It is indicated for the short-term treatment of obesity when used as an 'add-on' to behavior modifications such a diet and exercise. Phentermine is classified as an anorexiant stimulant and is chemically similar to amphetamines. We simply have case studies saying that it is possible and does happen from time to time. If the test isn't looking for phentermine, it still may produce a false-positive for amphetamines, although how often this occurs isn't well documented. Overall, if the drug test you are being administered is looking for phentermine, and you took your last dose on a Friday, there is a good chance it will be detectable on Monday (~3 days). more acidic) than normal, phentermine may be eliminated in as quick as 2-3 days. Some studies report that the half-life can decrease to 7-8 hours under acidic urinary conditions. It is important to note that phentermine elimination is increased the more acidic the urine is. This is right in line with how long studies report other amphetamine drugs being detectable (generally listed at 4-5 days). This would translate to phentermine being detectable for 4-6 days after your last dose. After around 5 to 6 half-lives, most drugs are no longer detectable on standard urinalysis tests.īased on published pharmacokinetic data on phentermine, it is primarily eliminated by the kidneys and has a half-life between 19-24 hours. The elimination half-life of a drug is typically a good indicator of how long it is detectable (although not always). In regard to how long it will last, or be detectable in the urine, depends on a number of factors including: ![]() Urine Drug Screening: Practical Guide for Clinicians Even if it not being specifically looked for on a urine drug test, it can produce a positive reading for amphetamines, according to most studies on the matter.Ī commonly referenced guide on urine drug screening, Urine Drug Screening: Practical Guide for Clinicians, specifically lists phentermine and other related stimulants as commonly causing 'false-positives' for amphetamine: Unfortunately, other stimulants, anorexiants, and chemically related compounds (e.g., pseudoephedrine), have been shown to produce false-positive results, making the amphetamine assay one of the most difficult tests to interpret. Phentermine (Adipex-P) is a stimulant, chemically and pharmacologically related to amphetamines (e.g. ![]() It may be eliminated from the body more quickly under acidic urinary conditions. Phentermine is detectable in the urine, anywhere from 2 to 6 days.
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